Temperature, Humidity and Climate

Ok this is a random, but have tests ever been done on the pancreas that are temperature driven?   

Humidity and climate?  Since the Diabetes belt is so warm and humid. Conversly, the Arctic people, who have a high rate of diabetes, have a lot of cold temperatures, so maybe the inflammation of the gut is a coping mechanism.

They both have diets high in fish, because of their proximity to the coast.

There's a lot of heat in the summer and longer warm periods for the Diabetes Belt, so higher metabolisms.  More open pores and sweating, gradually favoring larger bodies.  This doesn't correlate however with the Arctic people's because they have closed pores and smaller bodies.

Inflammation and Diabetes

So it's been shown that inflammation causes some cancers or plays a role in cancer.  I think this could be applied to diabetes. 

Does Inflammation Cause Cancer?

To me this article seems like it's saying that the E2F-1 could either cause inflammation or cancer.  So not a great diagnosis that is for a cure, but really just a helpful observation.  How does this affect diabetes?   What are these E2F-1, really and can we just get rid of them because they are causing us so much problems? I'm sure they are present and have a hand in causing diabetes.

Study Ties Inflammation, Gut Bacteria to Type 1 Diabetes

The study found that people with type 1 diabetes had significantly more inflammation in the mucous membrane of the gut. ... In type 1 diabetes, the body's immune system mistakenly attacks healthy cells in the body. Specifically, the disease causes the destruction of insulin-producing islet cells.